Flag of the European Union EU Clinical Trials Register Help

Clinical trials for Antiarrhythmic Drug

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   43881   clinical trials with a EudraCT protocol, of which   7295   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
    How to search [pdf]
    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
    Advanced Search: Search tools
     
    23 result(s) found for: Antiarrhythmic Drug. Displaying page 1 of 2.
    1  2  Next»
    EudraCT Number: 2021-004865-11 Sponsor Protocol Number: IV-FLEC Start Date*: 2022-03-21
    Sponsor Name:Win Medica Pharmaceuticals S.A.
    Full Title: Comparison of the effectiveness of IntraVenous FLECainide plus oral ranolazine versus intravenous flecainide alone in the cardioversion of recent onset atrial fibrillation – a randomized, prospecti...
    Medical condition: Restoration of sinus rhythm in patients with recent AF onset
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2012-000833-38 Sponsor Protocol Number: ISIS329993-CS6 Start Date*: 2012-06-19
    Sponsor Name:Isis Pharmaceuticals, Inc.
    Full Title: A Phase 2 Study to Assess the Antiarrhythmic and Symptomatic Effect of the Second Generation Antisense Oligonucleotide ISIS 329993 Targeting CRP in Patients with Paroxysmal Atrial Fibrillation
    Medical condition: Atrial fibrillation (AF)
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10003658 Atrial fibrillation PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2013-004456-38 Sponsor Protocol Number: XEN-D0103-CL-05 Start Date*: 2014-04-11
    Sponsor Name:Xention Limited
    Full Title: A double blind, randomised, placebo-controlled, crossover study assessing the use of XEN D0103 in patients with paroxysmal atrial fibrillation and implanted pacemakers allowing continuous beat-to-b...
    Medical condition: Paroxysmal atrial fibrillation
    Disease: Version SOC Term Classification Code Term Level
    16.1 100000004849 10034039 Paroxysmal atrial fibrillation LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2018-002103-33 Sponsor Protocol Number: 1080719 Start Date*: 2019-02-26
    Sponsor Name: AZ Sint-Jan Brugge-Oostende AV
    Full Title: Pulmonary vein isolation with versus without continued antiarrhythmic drug treatment in subjects with persistent atrial fibrillation: a prospective multi-centre randomized controlled clinical study...
    Medical condition: Symptomatic persistent atrial fibrillation: atrial fibrillation, that lasts longer than 7 days, including episodes that are terminated by cardioversion, either with drugs or by direct current cardi...
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004849 10071667 Persistent atrial fibrillation LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Ongoing) DK (Completed) ES (Ongoing) FR (Ongoing)
    Trial results: View results
    EudraCT Number: 2008-001384-11 Sponsor Protocol Number: captaf Start Date*: 2008-04-03
    Sponsor Name:
    Full Title: Catheter Ablation compared with Pharmacological Therapy for Atrial Fibrillation – the CAPTAF trial
    Medical condition: To study the effect of catheter ablation (using CE marked products) on the quality of life an in patients with atrial fibrillation depsite treatment with conevntional antiarrhythmic medical therapy...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10066664 Recurrent symptomatic atrial fibrillation LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2012-005292-14 Sponsor Protocol Number: not_applicable Start Date*: 2013-01-09
    Sponsor Name:Heikki Swan
    Full Title: Dantrolene in catecholaminiergic polymorphic ventricular tachycardia
    Medical condition: Catecholaminergic polymorphic ventricular tachycardia
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004849 10036095 Polymorphic ventricular tachycardia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2012-003034-16 Sponsor Protocol Number: FNOL-IVA-ICD Start Date*: 2014-05-12
    Sponsor Name:University Hospital Olomouc
    Full Title: Antiarrhythmic and antiremodelation effects of ivabradin in ICD carriers
    Medical condition: Heart failure
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2018-001518-13 Sponsor Protocol Number: 10407 Start Date*: 2018-11-12
    Sponsor Name:Maatschap Cardiologie Zwolle
    Full Title: Comparison between treatment with catheter ablation or anti-arrhythmic drugs (sotalol or combination of verapamil and flecainide) of patients with benign ventricular premature beats and ventricular...
    Medical condition: Premature ventricular beats, ventricular ectopy, ventricle tachycardia
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2017-004202-18 Sponsor Protocol Number: CRAFT Start Date*: 2018-01-30
    Sponsor Name:Fundación Interhospitalaria para la Investigación Cardiovascular
    Full Title: CRioablation vs Antiarrhythmic Drugs for Persistent Atrial Fibrillation Trial (CRAFT)
    Medical condition: Recurrent Persistent Atrial Fibrillation
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004849 10071667 Persistent atrial fibrillation LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2018-002979-17 Sponsor Protocol Number: K620 Start Date*: 2018-12-17
    Sponsor Name:Ruprecht-Karls University Heidelberg Medical Faculty, University Hospital
    Full Title: Use of doxapram as a new antiarrhythmic drug for a specific therapy of atrial fibrillation
    Medical condition: Paroxysmal or persistent, non-valvular, atrial fibrillation
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10003658 Atrial fibrillation PT
    20.0 10007541 - Cardiac disorders 10034039 Paroxysmal atrial fibrillation LLT
    20.0 10007541 - Cardiac disorders 10071667 Persistent atrial fibrillation LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2011-002532-12 Sponsor Protocol Number: IDE:G050233 Start Date*: 2011-10-27
    Sponsor Name:MAYO CLINIC
    Full Title: Catheter Ablation Versus Antiarrhythmic Drug Therapy for Atrial Fibrillation Trial (CABANA)
    Medical condition: Atrial fibrillation
    Disease: Version SOC Term Classification Code Term Level
    14.1 10007541 - Cardiac disorders 10003658 Atrial fibrillation PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed) DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2010-022947-39 Sponsor Protocol Number: CV203-010 Start Date*: 2011-03-18
    Sponsor Name:Bristol-Myers Squibb International Corporation
    Full Title: Randomized, Double-Blind, Placebo-Controlled, 4-Way Crossover Study to Evaluate the Safety, Tolerability and Effect on Atrial Fibrillation Burden of BMS-914392 in Patients with Paroxysmal Atrial Fi...
    Medical condition: Atrial Fibrillation
    Disease: Version SOC Term Classification Code Term Level
    14.1 10007541 - Cardiac disorders 10003661 Atrial fibrillation paroxysmal LLT
    14.1 10007541 - Cardiac disorders 10034039 Paroxysmal atrial fibrillation LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2006-005804-15 Sponsor Protocol Number: EFC4968 Start Date*: 2007-04-11
    Sponsor Name:sanofi-aventis recherche & développement
    Full Title: Randomized double blind trial to evaluate the efficacy and safety of dronedarone (400 mg BID) versus amiodarone (600 mg daily for 28 days then 200 mg daily thereafter) for at least 6 months for the...
    Medical condition: Atrial Fibrillation
    Disease: Version SOC Term Classification Code Term Level
    9.1 10003658 Atrial fibrillation LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed) DE (Completed) SE (Completed) BE (Completed) FI (Completed) EE (Completed) AT (Completed) IT (Completed) NL (Completed) PL (Completed)
    Trial results: View results
    EudraCT Number: 2007-003455-36 Sponsor Protocol Number: D3190C00005 Start Date*: 2007-12-21
    Sponsor Name:AstraZeneca AB
    Full Title: A Multi-centre, Double-blind, Randomised, Placebo-controlled, Single-dose, Phase II Study to Assess the Effects on Atrial and Ventricular Refractoriness and Haemodynamics of an Intravenous Infusion...
    Medical condition: AZD1305 is a novel antiarrhythmic agent being developed for treatment of atrial fibrillation (AF). Potential indications include conversion of AF to sinus rhythm (SR) and maintenance of SR after c...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Prematurely Ended) SE (Prematurely Ended) DK (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2014-000530-29 Sponsor Protocol Number: CONVERT-AF Start Date*: 2014-08-19
    Sponsor Name:University Hospital Basel
    Full Title: Canakinumab for the Prevention of Recurrences After Electrical Cardioversion in Patients With Persistent Atrial Fibrillation (CONVERT-AF) Trial - A Randomized Double Blind Placebo Controlled Study
    Medical condition: Atrial Fibrillation
    Disease: Version SOC Term Classification Code Term Level
    16.1 10007541 - Cardiac disorders 10003658 Atrial fibrillation PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2016-002956-25 Sponsor Protocol Number: MAS-OLE-16-003 Start Date*: 2016-11-18
    Sponsor Name:FONDAZIONE POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI IRCCS UNIVERSITA' CATTOLICA DEL SACRO CUORE
    Full Title: Olevia for the prevention of atrial fibrillation post heart valve-surgery.
    Medical condition: POST-OPERATIVE ATRIAL FIBRILLATION
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004849 10016566 Fibrillation atrial LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2015-001529-18 Sponsor Protocol Number: LGN-VN-003 Start Date*: 2015-08-18
    Sponsor Name:Laguna Pharmaceuticals, Inc.
    Full Title: RESTORE SR: A multi-center, Randomized, double-blind, placebo-controlled study to Evaluate the Safety and efficacy of a single oral dose of vanoxerine for The conversion Of subjects with REcent ons...
    Medical condition: Recent atrial fibrillation (AF) or atrial flutter (AFL)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Prematurely Ended) NL (Ongoing) PL (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2015-003077-15 Sponsor Protocol Number: EIG-LNF-002 Start Date*: 2015-11-23
    Sponsor Name:Eiger BioPharmaceuticals
    Full Title: A Phase 2, Open-Label Study of the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamic Activity of Titrating-Dose Lonafarnib in Combination with Ritonavir in Patients Chronically Infected w...
    Medical condition: Chronic Hepatitis D Virus (HDV) Infection.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2007-005625-29 Sponsor Protocol Number: VERI-305-AMIO Start Date*: 2008-03-06
    Sponsor Name:Cardiome Pharma Corp.
    Full Title: A Phase III Prospective, Randomized, Double-Blind, Active-Controlled, Multi-Center, Superiority Study of Vernakalant Injection versus Amiodarone in Subjects with Recent Onset Atrial Fibrillation
    Medical condition: Treatment of Atrial fibrillation (AF). AF is the most common arrhythmia encountered in clinical practice. It is usually associated with age and general physical condition, rather than with a speci...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10003658 Atrial fibrillation LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) SE (Completed) FR (Completed) LT (Completed) EE (Completed) DK (Completed) CZ (Completed) FI (Completed) SK (Completed) LV (Completed) NL (Completed)
    Trial results: View results
    EudraCT Number: 2015-002516-33 Sponsor Protocol Number: NCT01420393 Start Date*: 2015-09-03
    Sponsor Name:University of Ottawa Heart Institute
    Full Title: A Randomized Ablation-based atrial Fibrillation rhythm control versus rate control Trial in patients with heart failure and high burden Atrial Fibrillation
    Medical condition: The study is comparing two accepted treatment methods (rhythm control-Catheter ablation with or without anti-arrhythmic drug control of maintaining sinus rhythm versus rate controls with medical th...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    Download Options:
    Number of Trials to download:
    Download Content:
    Download Format:
    Note, where multi-state trials are shown in search results, selecting "Full Trial details" will download full information for each of the member states/countries involved in the trial.
    1  2  Next»
    Query did not match any studies.
    For support, Contact us.
    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

    European Medicines Agency © 1995-Sun May 19 21:11:46 CEST 2024 | Domenico Scarlattilaan 6, 1083 HS Amsterdam, The Netherlands
    EMA HMA